疫情暴发至今，新型冠状bingdu.html target=_blank class=infotextkey>病毒（Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoV-2）在人类中表现出极强的infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/PS.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML tinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARget=_blank class=infotextkey>PS://www.169zx.com/tag/chuanbo.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML tinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARget=_blank class=infotextkey>传播能力。近日，通过将Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoV-2和2003年暴发的Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoV（严重急性呼吸综合征冠状bingdu.html target=_blank class=infotextkey>病毒）之间的进化动态进行比较，科研人员惊讶地发现，Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoV-2在人类中infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/PS.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML tinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARget=_blank class=infotextkey>PS://www.169zx.com/tag/chuanbo.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML tinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARget=_blank class=infotextkey>传播初期就具有高度适应性，其程度类似于当年Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoVinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/liuxing.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>流行的晚期。

当地时间5月2日，生物科学预印本平台bioRxiv在线发表了题为“Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoV-2 is well adapted for humans. What does this mean for re-emergence?”的研究论文，研究团队来自加拿大英属biya.html target=_blank class=infotextkey>哥伦比亚大学、美国麻省理工学院-哈佛大学博德研究所（Broad instinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/IT.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ITute）斯坦利精神病学研究中心、加拿大infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/yiliao.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>医疗infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/qiye.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>企业Fusion Genominfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/ic.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ics等，通讯作者为英属biya.html target=_blank class=infotextkey>哥伦比亚大学生物多样性研究中心的Shing Hei Zhan与博德研究所的Alina Chan。
 

研究结果表明，2019年末首次检测到Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoV-2时，它已经对人类具有高度的适应性，其程度类似于infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/liuxing.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>流行晚期的Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoV。同时，研究人员尚未检测到人类适应性较差的类Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoV-2bingdu.html target=_blank class=infotextkey>病毒的进化前体或进化分支。

这意味着，新冠bingdu.html target=_blank class=infotextkey>病毒在infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/PS.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML tinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARget=_blank class=infotextkey>PS://www.169zx.com/tag/chuanbo.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML tinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARget=_blank class=infotextkey>传播之初就具有极强的人类适应性和传染性。因此，研究人员强调，其二次暴发的可能性较大，应引起infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/PS.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML tinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARget=_blank class=infotextkey>PS://www.169zx.com/tag/guoji.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML tinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARget=_blank class=infotextkey>国际infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/PS.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML tinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARget=_blank class=infotextkey>PS://www.169zx.com/tag/shehinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/ui.html target=_blank class=infotextkey>ui.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML tinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARget=_blank class=infotextkey>社会更大的infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/guanzhu.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>关注，以明确其来源并防止二次暴发。

 

作者们警告，如果具有相似的人类infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/PS.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML tinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARget=_blank class=infotextkey>PS://www.169zx.com/tag/chuanbo.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML tinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARget=_blank class=infotextkey>传播性和适应性，那么任何现有的Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoV-2祖bingdu.html target=_blank class=infotextkey>病毒库都是特别危险的。

作者们还强调，新冠bingdu.html target=_blank class=infotextkey>病毒的S蛋白（刺突糖蛋白）有可能在蝙蝠或多种中间宿主中自然进化出其广泛的物种向性（specinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/IE.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>IEs tropism），即它可能与多物种的受体结合。

对此，研究人员提出建议，应扩大采样范围，从市场、农场和野生动物中收集Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoV-2样bingdu.html target=_blank class=infotextkey>病毒。此外，应该检查2019年底前几个月的人类样本中Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoV-2样bingdu.html target=_blank class=infotextkey>病毒或Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoV-2反应抗体，以检测bingdu.html target=_blank class=infotextkey>病毒在人类infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/PS.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML tinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARget=_blank class=infotextkey>PS://www.169zx.com/tag/shehinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/ui.html target=_blank class=infotextkey>ui.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML tinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARget=_blank class=infotextkey>社会中infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/liuxing.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>流行的前体。

新冠bingdu.html target=_blank class=infotextkey>病毒高度适应于人类，需高度警惕二次暴发

对于新冠bingdu.html target=_blank class=infotextkey>病毒而言，研发特定的抗bingdu.html target=_blank class=infotextkey>病毒药物、抗体或疫苗所用的时间长短取决于bingdu.html target=_blank class=infotextkey>病毒基因或蛋白质的进化速度和infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/PS.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML tinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARget=_blank class=infotextkey>PS://www.169zx.com/tag/chuanbo.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML tinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARget=_blank class=infotextkey>传播程度。

日前，包括钟南山院士在内的多个专家团队已经指出，新冠bingdu.html target=_blank class=infotextkey>病毒在infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/PS.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML tinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARget=_blank class=infotextkey>PS://www.169zx.com/tag/chuanbo.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML tinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARget=_blank class=infotextkey>传播过程中发生了广泛的变异，现在已经非常适应在人体内生存。之前的一些医学报告指出，Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoV-2基因组似乎稳定下来，其在人体的适应压力不大，这对诊断、疫苗和治疗学的发展都是好兆头。

为了更好地了解Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoV-2基因组的稳定性，研究人员对Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoV-2和Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoV之间的进化动力学进行了并行比较。

研究人员收集了11个Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoVinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/liuxing.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>流行早期至中期的基因组，32个Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoVinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/liuxing.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>流行晚期的基因组以及46个Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoV-2基因组。

令人惊讶的是，与Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoV相比，Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoV-2表现出较低的遗传多样性，而Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoV在其infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/liuxing.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>流行的早期到中期具有相当大的遗传多样性。相比之下，Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoV-2的遗传多样性与晚期infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/liuxing.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>流行Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoV的遗传多样性更为相似。

Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoV和Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoV-2遗传差异的比较，在同样的时间范围内，Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoV-2（红色）的遗传多样性比早期到中期Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoV（蓝色）的少

此前对Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoV的研究表明，在早期和中期infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/PS.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML tinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARget=_blank class=infotextkey>PS://www.169zx.com/tag/chuanbo.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML tinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARget=_blank class=infotextkey>传播阶段，Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoV受到的选择压力（又称为进化压力，指外界施与一个生物进化过程的压力）最大，并在infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/liuxing.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>流行晚期时选择压力减弱。在从蝙蝠、果子狸infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/PS.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML tinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARget=_blank class=infotextkey>PS://www.169zx.com/tag/chuanbo.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML tinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARget=_blank class=infotextkey>传播到人类以及接下来的人际infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/PS.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML tinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARget=_blank class=infotextkey>PS://www.169zx.com/tag/chuanbo.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML tinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARget=_blank class=infotextkey>传播的过程中，一系列适应infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/huodong.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>活动使bingdu.html target=_blank class=infotextkey>病毒具有高度传染性，这一高传染性主导了其晚期infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/liuxing.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>流行阶段。

非同义和同义替代率（dN和dS）通常用于模拟bingdu.html target=_blank class=infotextkey>病毒S蛋白（在bingdu.html target=_blank class=infotextkey>病毒入侵人体时与宿主受体结合并影响宿主特异性）等基因经历的选择压力。研究人员在2020年1月、2月和3月每个月从不同的地理位置采样50个Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoV-2基因组，他们发现对于bingdu.html target=_blank class=infotextkey>病毒S蛋白、Orf3a和Orf1a基因而言，新冠bingdu.html target=_blank class=infotextkey>病毒中的dN和dS与Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoV晚期infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/liuxing.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>流行时的情况更相似。

infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/liuxing.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>流行早期至中期的Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoV、infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/liuxing.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>流行晚期的Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoV以及2020年1月至3月的Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoV-2样本中S蛋白等基因的dN和dS对比情况这些研究结果意味着，Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoV-2在暴发之初就已经高度适应于人类，并表现出极强的infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/PS.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML tinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARget=_blank class=infotextkey>PS://www.169zx.com/tag/chuanbo.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML tinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARget=_blank class=infotextkey>传播能力。

研究人员还表示，在人类和动物中，一种更早期的、适应性较差的共同祖bingdu.html target=_blank class=infotextkey>病毒尚未被找到，其前体或分支也是缺失的。这表明该bingdu.html target=_blank class=infotextkey>病毒以一种高人类适应性的形式进入人类infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/PS.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML tinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARget=_blank class=infotextkey>PS://www.169zx.com/tag/shehinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/ui.html target=_blank class=infotextkey>ui.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML tinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARget=_blank class=infotextkey>社会，这也意味着在不久的将来再次出现Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoV-2的风险较高，且其后果可能较严重。

自然界进化可能使新冠bingdu.html target=_blank class=infotextkey>病毒与多物种结合，应扩大采样范围

迄今为止，研究人员仍不确定新冠bingdu.html target=_blank class=infotextkey>病毒的中间宿主是什么。此前的研究发现，与Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoV-2关系最密切的冠状bingdu.html target=_blank class=infotextkey>病毒是蝙蝠冠状bingdu.html target=_blank class=infotextkey>病毒RaTG13，而从马来infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/xi.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>西亚穿山甲中分离出的一种冠状bingdu.html target=_blank class=infotextkey>病毒的遗传序列与Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoV-2有高达91%的同源性，因此，研究人员认为，就目前而言，蝙蝠是新冠bingdu.html target=_blank class=infotextkey>病毒起源、穿山甲是中间宿主的可能性较大。

此外，研究人员指出，新冠bingdu.html target=_blank class=infotextkey>病毒的S蛋白有可能在蝙蝠或多种中间宿主中自然进化出其广泛的物种向性，即它可能与多物种的受体结合。

此前有研究预测，Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoV-2的S蛋白可能与100多种不同物种的ACE2（血管紧张素转化酶2，新冠bingdu.html target=_blank class=infotextkey>病毒的人类受体）结合，并且比Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoV对于蝙蝠和人类ACE2的结合性都强。

因此，尽管尚未发现蝙蝠冠状bingdu.html target=_blank class=infotextkey>病毒具有Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoV-2样的S蛋白RBD（受体结合域），但新冠bingdu.html target=_blank class=infotextkey>病毒很可能在自然界中进化，并且可以以最佳水平与不同物种的同一受体结合。研究人员建议，

应从更多物种中进行冠状bingdu.html target=_blank class=infotextkey>病毒采样，从而更好地掌握携带与Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoV-2相似的RBD的冠状bingdu.html target=_blank class=infotextkey>病毒的物种范围，明确其中间宿主。

为了寻找有关新冠bingdu.html target=_blank class=infotextkey>病毒中间宿主的线索，研究人员还分析了有关Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoV-2如何进化和适应人类infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/PS.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML tinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARget=_blank class=infotextkey>PS://www.169zx.com/tag/chuanbo.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML tinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARget=_blank class=infotextkey>传播的最新发现，并研究了武汉华南海鲜市场的infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/PS.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML tinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARget=_blank class=infotextkey>PS://www.169zx.com/tag/huanjing.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML tinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARget=_blank class=infotextkey>环境样本。

结果表明，2020年1月份在市场发现的bingdu.html target=_blank class=infotextkey>病毒分离株不太可能起源于中间动物宿主，而是最有可能来自被Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoV-2感染的人，他们可能是市场里的卖家或顾客。

为了追踪新冠bingdu.html target=_blank class=infotextkey>病毒祖先bingdu.html target=_blank class=infotextkey>病毒株，找出其中间宿主，研究人员提出了以下建议：

1、从市场、农场和野生动物中收集Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoV-2样bingdu.html target=_blank class=infotextkey>病毒；

2、检查2019年底前几个月的人类样本中Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoV-2样bingdu.html target=_blank class=infotextkey>病毒或Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoV-2反应抗体，以检测bingdu.html target=_blank class=infotextkey>病毒在人类infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/PS.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML tinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARget=_blank class=infotextkey>PS://www.169zx.com/tag/shehinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/ui.html target=_blank class=infotextkey>ui.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML tinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARget=_blank class=infotextkey>社会infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/liuxing.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>流行的前体；

3、对更多早期的Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoV-2分离株进行测序，特别是早期分离株，可以识别出人类适应性较弱的祖细胞的分支；

4、评估infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/PS.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML tinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARget=_blank class=infotextkey>PS://www.169zx.com/tag/shinfotextkey>ipin2.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML tinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARget=_blank class=infotextkey>食品经营者和动物贸易商的患病率相较普通人是否过高，以确定动物贸易中是否存在Sinfotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/AR.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>ARS-CoV-2祖先bingdu.html target=_blank class=infotextkey>病毒株；

此外，应更广泛地限制人类infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/huodong.infotextkey>TPs://www.169zx.com/tag/HTinfotextkey>TPS.html target=_blank class=infotextkey>HTinfotextkey>TPS://www.169zx.com/tag/HTML.html target=_blank class=infotextkey>HTML target=_blank class=infotextkey>活动，减少人类与野生动物及其栖息地的频繁或长期接触。